BDBM50460879 CHEMBL4228441

SMILES CCC[C@H](N1C\C(NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)=N\N(C)C)C(=O)Nc1cccc(c1)-c1cnn(C)c1

InChI Key InChIKey=NXHYJWBLLSRBTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460879   

TargetKallikrein-7(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50460879(CHEMBL4228441)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50460879(CHEMBL4228441)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human KLK5 using Boc-Val-Pro-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTrypsin(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50460879(CHEMBL4228441)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed