BDBM50461326 CHEMBL4227754

SMILES CC1=C(C(NC(=O)N1)c1ccc(F)c(CCC(=O)NCC2(CO)CC2)c1)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=MRFFVYCGQCPHFX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50461326   

TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461326(CHEMBL4227754)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461326(CHEMBL4227754)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhodopsin kinase GRK1(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50461326(CHEMBL4227754)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GRK1 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed