BDBM50462114 CHEMBL2311600

SMILES COc1ccc(cc1)C(CN(C)C)[Si]1(O)CCCC1

InChI Key InChIKey=NPHHKEQIFWZXEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462114   

TargetSodium-dependent noradrenaline transporter(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462114(CHEMBL2311600)
Affinity DataIC50: 275nMAssay Description:Inhibition of human NET expressed in MDCK cells assessed as decrease in [3H]-noradrenaline reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462114(CHEMBL2311600)
Affinity DataIC50: 707nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells assessed as decrease in [3H]-dopamine reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462114(CHEMBL2311600)
Affinity DataIC50: 904nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as decrease in [3H]-serotonin reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed