BDBM50462118 CHEMBL4243296

SMILES C(N1CC[Si]2(CCCc3ccccc23)CC1)c1ccccc1

InChI Key InChIKey=TYJPHBPGOHKHLW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50462118   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50462118(CHEMBL4243296)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to Guinea pig brain Sigma1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50462118(CHEMBL4243296)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462118(CHEMBL4243296)
Affinity DataKi:  243nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462118(CHEMBL4243296)
Affinity DataKi:  243nMAssay Description:Binding affinity to rat liver Sigma2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed