BDBM50462129 CHEMBL4244166

SMILES CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(cc1)C#CC(=O)N[C@H]1C[C@H](N(C1)C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(=O)N[C@@H]1CCCc2ccccc12)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc12

InChI Key InChIKey=SOUZAGJRYQSXAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462129   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462129(CHEMBL4244166)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged XIAP BIR3 domain (241 to 356 residues) (unknown origin) using fluorescein labeled SMAC peptide as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462129(CHEMBL4244166)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His-tagged XIAP BIR2-3 domain (125 to 356 residues) C202A/C213G mutant (unknown origin) using fluorescein labeled SMAC pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed