BDBM50463234 CHEMBL4243348

SMILES Fc1cccc(Nc2nc(NC3CCNCC3)nc(n2)C#N)c1

InChI Key InChIKey=AWOBKJOFJAEFMO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463234   

TargetCathepsin K(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463234(CHEMBL4243348)
Affinity DataIC50: 100nMAssay Description:Inhibition of human cathepsin K using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin S(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463234(CHEMBL4243348)
Affinity DataIC50: 400nMAssay Description:Inhibition of human cathepsin S using Z-LR-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463234(CHEMBL4243348)
Affinity DataIC50: 400nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50463234(CHEMBL4243348)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC as substrate after 30 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed