BDBM50463707 CHEMBL4237289

SMILES Cc1cc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)c2c(N)onc2n1

InChI Key InChIKey=KCCWVRNMXATDGV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463707   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463707(CHEMBL4237289)
Affinity DataIC50: 5nMAssay Description:Inhibition of human FLT3 using biotin labeled substrate after 1 hr by HTFR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463707(CHEMBL4237289)
Affinity DataIC50: 25nMAssay Description:Inhibition of human KDR using biotin labeled substrate after 1 hr by HTFR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463707(CHEMBL4237289)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDGFRbeta using biotin labeled substrate after 1 hr by HTFR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed