BDBM50463798 CHEMBL4238190
SMILES COCCn1cc(cn1)-c1nn(C2CCCN(C2)C(=O)CC#N)c2ncnc(N)c12
InChI Key InChIKey=MHEOEIBMITWKMP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50463798
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of recombinant human GST-tagged TYK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 497nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 697nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair