BDBM50463849 CHEMBL4250626

SMILES OC(=O)c1ccc(cc1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F

InChI Key InChIKey=FXZCBPORQDEBAL-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463849   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
TBA

Curated by ChEMBL

LigandBDBM50463849(CHEMBL4250626)Copy SMILESCopy InChI

Affinity DataIC50: 20nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
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TargetTransient receptor potential cation channel subfamily M member 8(Rat)
TBA

Curated by ChEMBL

LigandBDBM50463849(CHEMBL4250626)Copy SMILESCopy InChI

Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mi...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL