BDBM50465232 CHEMBL4280922::US10766903, Example 4

SMILES C[C@H](CC(=O)N1CCC(O)(Cn2cnc(Nc3ccccc3)cc2=O)CC1)c1ccccc1

InChI Key InChIKey=WFMXEEPSEBBFMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465232   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465232(CHEMBL4280922 | US10766903, Example 4)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of USP7 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465232(CHEMBL4280922 | US10766903, Example 4)
Affinity DataIC50: 1.01E+5nMAssay Description:USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent