BDBM50465234 CHEMBL4283787::US10766903, Example 46

SMILES Cn1nc2c(ncn(CC3(O)CCN(CC3)C(=O)C[C@H](c3ccccc3)C(F)(F)F)c2=O)c1-c1ccc(CN)cc1

InChI Key InChIKey=RLPQYKGBXQQARM-JOCHJYFZSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50465234   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465234(CHEMBL4283787 | US10766903, Example 46)
Affinity DataIC50:  22nMAssay Description:Inhibition of USP7 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465234(CHEMBL4283787 | US10766903, Example 46)
Affinity DataIC50:  22nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate by fluorescence based SPR analysisMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465234(CHEMBL4283787 | US10766903, Example 46)
Affinity DataIC50: <250nMAssay Description:USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...More data for this Ligand-Target Pair