BDBM50465267 CHEMBL4287027::US11299480, Example 40

SMILES C[C@@H](N(C)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(cc1Cl)C(O)=O

InChI Key InChIKey=SDGPIYMLYGLENB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465267   

TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii

US Patent
LigandPNGBDBM50465267(CHEMBL4287027 | US11299480, Example 40)
Affinity DataIC50: 4.10E+3nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2022
Entry Details
US Patent

TargetSignal transducer and activator of transcription 3(Mouse)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM50465267(CHEMBL4287027 | US11299480, Example 40)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of STAT3 DNA binding activity in mouse NIH/3T3 nuclear extract preincubated for 30 mins followed by [32P]hSIE addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed