BDBM50465526 CHEMBL4294239

SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)NC3CCCCC3)cc12)C(=O)NS(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=BCMLBMIEKQMGLP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465526   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50465526(CHEMBL4294239)
Affinity DataEC50:  350nMAssay Description:Partial agonist activity at human PPARgamma LBD expressed HEK293T cells after 12 to 14 hrs by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50465526(CHEMBL4294239)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed