BDBM50465643 CHEMBL4284657

SMILES CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(N=C(N)N)cc1)C(=O)N1CCCC1c1nc2ccccc2[nH]1

InChI Key InChIKey=FGLYVGSXVVJJFG-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465643   

TargetBaculoviral IAP repeat-containing protein 2(Human)
University of California Riverside

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465643BDBM50465643(CHEMBL4284657)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of AVPIAQKSEK-biotin from cIAP1 BIR3 (unknown origin) after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California Riverside

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465643BDBM50465643(CHEMBL4284657)
Affinity DataIC50: 5.94E+3nMAssay Description:Displacement of AVPIAQKSEK-biotin from N-terminal His-tagged human recombinant XIAP BIR3 (253 to 347 residues) expressed in Escherichia coli BL21(DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
University of California Riverside

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465643BDBM50465643(CHEMBL4284657)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of AVPIAQKSEK-biotin from cIAP2 BIR3 (unknown origin) after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
University of California Riverside

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50465643BDBM50465643(CHEMBL4284657)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to N-terminal His-tagged human recombinant XIAP BIR3 (253 to 347 residues) expressed in Escherichia coli BL21(DE3) Gold by isotherma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed