BDBM50466025 CHEMBL4288656

SMILES Nc1cc(-c2ccc(s2)C(=O)c2cc(F)c(F)c(O)c2F)c(F)cc1F

InChI Key InChIKey=HHROZDYJKDQBPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466025   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466025(CHEMBL4288656)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466025(CHEMBL4288656)
Affinity DataIC50: 27nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed