BDBM50466801 CHEMBL4286522

SMILES Cc1[nH][n+](C)c2c1-c1cnc(N)c(c1)O[C@H](C)c1cc(F)ccc1C(=O)N(C)C2

InChI Key InChIKey=ASQDMAQHZGURLM-UHFFFAOYSA-O

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50466801   

TargetALK tyrosine kinase receptor(Human)
Taibah University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466801BDBM50466801(CHEMBL4286522)
Affinity DataKi: <0.200nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Taibah University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466801BDBM50466801(CHEMBL4286522)
Affinity DataKi:  0.290nMAssay Description:Inhibition of L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50466801BDBM50466801(CHEMBL4286522)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of wild type EML4/ALK (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50466801BDBM50466801(CHEMBL4286522)
Affinity DataIC50: 14nMAssay Description:Inhibition of wild type EML4/ALK L1196M mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed