BDBM50466805 CHEMBL4282530

SMILES COc1cc2c(Nc3ccc(cc3)C(=O)Nc3ccccc3)ncnc2cc1O

InChI Key InChIKey=YQTIZDYSQKQTBQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50466805   

TargetAurora kinase B(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466805(CHEMBL4282530)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466805(CHEMBL4282530)
Affinity DataIC50: 41nMAssay Description:Inhibition of Aurora B in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466805(CHEMBL4282530)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant aurora 2 (unknown origin) expressed in Sf21 insect cells incubated for 60 mins using [biotin LRRWSLGLRRWSLGLRRWSLGLRRWSLG s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466805(CHEMBL4282530)
Affinity DataIC50: 60nMAssay Description:Inhibition of Aurora A in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed