BDBM50466904 CHEMBL4286366
SMILES Cn1cc(C2CCN(CC2)C(=O)C2CCCC2)c2nc(NC(=O)c3cc(ccn3)C#N)ccc12
InChI Key InChIKey=JKWKGKZGJMIKOP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50466904
Affinity DataIC50: 357nMAssay Description:Inverse agonist activity at RORC2 in human Th17 cells assessed as inhibition of IL17A production after 6 days by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inverse agonist activity at human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cells assessed as inhibi...More data for this Ligand-Target Pair