BDBM50467198 CHEMBL4287064

SMILES COc1ccc(cc1)-c1nc(sc1C(=O)c1ccccc1)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=GCBYJNQEZBSRJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467198   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50467198(CHEMBL4287064)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50467198(CHEMBL4287064)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed