BDBM50467330 CHEMBL307950

SMILES Cc1cc(C)c(Nc2nc(Nc3ccc(cc3)C#N)ncc2C=C)c(C)c1

InChI Key InChIKey=OFZPTYFLZZXCJA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50467330   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 29nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 35nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 36nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 106nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y188C double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467330(CHEMBL307950)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed