BDBM50467345 CHEMBL308004
SMILES Cc1cnc(Nc2ccc(cc2)C#N)nc1Nc1c(C)cc(cc1C)C#N
InChI Key InChIKey=YALKQTNPKCPCSL-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50467345
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 162nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y188C double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair