BDBM50467350 CHEMBL4293640

SMILES Cc1cc(C)c(Nc2ccnc(Nc3ccc(Cl)cc3)n2)c(C)c1

InChI Key InChIKey=UKMJJMHWYKEQMZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50467350   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467350(CHEMBL4293640)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of wild-type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467350(CHEMBL4293640)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467350(CHEMBL4293640)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase Y181C mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467350(CHEMBL4293640)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase L100I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467350(CHEMBL4293640)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase Y188L mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467350(CHEMBL4293640)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase L100I/K103N double mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed