BDBM50467755 CHEMBL4291795

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1F)c1cc(Cc2ccc3OCCOc3c2)c2OCCc2c1O

InChI Key InChIKey=JRCJDHHDZPYFFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467755   

TargetSodium/glucose cotransporter 2(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50467755(CHEMBL4291795)
Affinity DataIC50: 3nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50467755(CHEMBL4291795)
Affinity DataIC50: 14nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed