BDBM50467798 CHEMBL4288225

SMILES COc1cc2c(nc(nc2cc1OC1CCCC1)N(C)C)N1CCN(CC1)C(=O)c1ccccc1

InChI Key InChIKey=MMJBJONSPGKZHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467798   

TargetToll-like receptor 9(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50467798(CHEMBL4288225)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50467798(CHEMBL4288225)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed