BDBM50468315 CHEMBL4294514

SMILES [H][C@]12Cc3c([C@H](C)N1C(=O)CN(CCC)C2=O)n(Cc1ccc(cc1)C(=O)NO)c1ccccc31

InChI Key InChIKey=PNSCXVKMXNVVCY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50468315   

TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50: 168nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic trifluoroacetyl lysine as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human recombinant HDAC10 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468315(CHEMBL4294514)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed