BDBM50469211 CHEMBL4283503
SMILES O=C(Nc1cncc(c1)-c1cc(cs1)-c1cccnc1)C1CC1
InChI Key InChIKey=FUSZCAJFRIHBLV-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50469211
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of DYRK1A in human HeLa cells harboring GFP-SF3b1-NT assessed as reduction in SF3b1 phosphorylation at T343 residue after 18 hrs by Wester...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human GST-tagged CLK1 (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substrate after 15 mins...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of human GST-tagged haspin expressed in baculovirus expression system in presence of 100 uM ATPMore data for this Ligand-Target Pair