BDBM50470413 CHEMBL4279795

SMILES [O-][N+](=O)c1ccc(Oc2ccc(\C=C3/SC(=O)N(C3=O)c3ccc(OCCCCN4CCN(CC5CC5)CC4)cc3)cc2)cc1

InChI Key InChIKey=JYNCKLFAJJPRMK-SJIPCVTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50470413   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50470413(CHEMBL4279795)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) using IkappaBalpha-derived 5FAMGRHDSGLDSMK-NH2 as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50470413(CHEMBL4279795)
Affinity DataIC50:  5.53E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current at -80 holding potential after 100 to 200 secs by whole cell a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed