BDBM50471869 CHEMBL133652

SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccccc2)C(=O)c2ccccc2C1=O

InChI Key InChIKey=QGANODRXZGAKQW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50471869   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sw 8 Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50471869(CHEMBL133652)
Affinity DataIC50: 500nMAssay Description:Concentration to inhibit 50% of Phosphodiesterase 4 (PDE-4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sw 8 Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50471869(CHEMBL133652)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity at Phosphodiesterase 4 by measuring displacement of (+/-)-[3H]- Rolipram to guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed