BDBM50472602 CHEMBL45336

SMILES CN(C)c1nc(CNCC2(F)CCN(CC2)C(=O)c2ccc(F)c(Cl)c2)ccc1C

InChI Key InChIKey=PJUIHPOKHRKRJO-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50472602   

Target5-hydroxytryptamine receptor 1A(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472602(CHEMBL45336)
Affinity DataKi:  0.316nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472602(CHEMBL45336)
Affinity DataEC50:  3.70nMAssay Description:In vitro effective concentration required to inhibit forskolin-stimulated cAMP levels in HA7 cells expressing human 5-HT1A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed