BDBM50474241 CHEMBL322256

SMILES C(OCc1ccccc1)[C@@H]1CC[C@H](O1)c1c[nH]cn1

InChI Key InChIKey=RETVAMKTDRMQFH-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50474241   

TargetHistamine H3 receptor(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataEC50:  9.55E+3nMAssay Description:Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataKi:  1.05E+4nMAssay Description:Compound was tested for H3 receptor competition binding using [3H]- Na-methylhistamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataEC50:  1.29E+4nMAssay Description:Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50474241(CHEMBL322256)
Affinity DataKi:  2.14E+4nMAssay Description:Histamine H4 receptor competition binding using [3H]Na-methylhistamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed