BDBM50474342 CHEMBL357268

SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2ccccc2)cc1

InChI Key InChIKey=UZCQCEODMVDIJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50474342   

TargetHistone deacetylase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50474342(CHEMBL357268)
Affinity DataIC50: 544nMAssay Description:Inhibition of HDAC1 (unknown origin) using p53 residues 379 to 382 [RHKK(Ac)] as fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50474342(CHEMBL357268)
Affinity DataIC50: 613nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50474342(CHEMBL357268)
Affinity DataIC50: 624nMAssay Description:Inhibition of HDAC3 (unknown origin) using p53 residues 379 to 382 [RHKK(Ac)] as fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50474342(CHEMBL357268)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed