BDBM50475004 CHEMBL369572

SMILES O=C(N1CCCCC1)N1CCn2cc(C3=C(C(=O)NC3=O)c3cnc4ncccn34)c3cccc(C1)c23

InChI Key InChIKey=ULXFFBWWZLAHEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50475004   

TargetGlycogen synthase kinase-3(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475004(CHEMBL369572)
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50475004(CHEMBL369572)
Affinity DataIC50: 53nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed