BDBM50475336 CHEMBL606959

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5(O)Cc1c4C[C@@]5(O)[C@@]6([H])Cc7ccc(O)c8O[C@@]([H])(c4[nH]c21)[C@]5(CCN6C)c78)ccc3O

InChI Key

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50475336   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50475336(CHEMBL606959)
Affinity DataKi:  7.70nMAssay Description:Inhibition of [3H]diprenorphine binding to human opioid receptor kappa 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50475336(CHEMBL606959)
Affinity DataKi:  64nMAssay Description:Inhibition of [3H]diprenorphine binding to rat Opioid receptor mu 1 expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50475336(CHEMBL606959)
Affinity DataKi:  98nMAssay Description:Inhibition of [3H]diprenorphine binding to rat Opioid receptor delta 1 expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50475336(CHEMBL606959)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity against rat Opioid receptor mu 1 expressed in C6 cells in [35S]-GTP-gamma S binding assay More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed