BDBM50476091 8,8''-Biskoenigine::CHEMBL434383

SMILES COc1cc2c([nH]c3c4C=CC(C)(C)Oc4c(C)cc23)c(c1O)-c1c(O)c(OC)cc2c1[nH]c1c3C=CC(C)(C)Oc3c(C)cc21

InChI Key InChIKey=DQRAEENKHHFBHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476091   

TargetCathepsin K(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50476091(CHEMBL434383 | 8,8''-Biskoenigine)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50476091(CHEMBL434383 | 8,8''-Biskoenigine)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of cathepsin B mediated osteoporotic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed