BDBM50476388 CHEMBL2113281

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2c(NC(=O)c4ccc5cc(C=O)c(C=O)cc5c4)cccc12)ccc3O

InChI Key

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50476388   

TargetDelta-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476388(CHEMBL2113281)
Affinity DataIC50: 0.460nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476388(CHEMBL2113281)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]diprenorphine from delta opioid receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476388(CHEMBL2113281)
Affinity DataIC50: 20nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum longitudinal muscleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476388(CHEMBL2113281)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]diprenorphine from mu opioid receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476388(CHEMBL2113281)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]diprenorphine from kappa opioid receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476388(CHEMBL2113281)
Affinity DataIC50: 215nMAssay Description:Ratio of IC50 of drug to naltrindole for delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed