BDBM50476454 CHEMBL233505

SMILES [H][C@]1(CCC[C@H](COC(=O)N2CCN(CC2)C2CCCCC2)N1S(=O)(=O)c1ccc(Cl)cc1)c1cc(F)ccc1F

InChI Key InChIKey=XRMGQEUJTZXKOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476454   

TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50476454(CHEMBL233505)
Affinity DataIC50: 28nMAssay Description:Inhibition of gamma secretase-mediated amyloid-beta peptid aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed