BDBM50476459 CHEMBL232886

SMILES [H][C@]1(CCC[C@H](COC(=O)N2CCN(CC3CC3)CC2C)N1S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=ZVFYYUNCJRTCOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476459   

TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50476459(CHEMBL232886)
Affinity DataIC50: 37nMAssay Description:Inhibition of gamma secretase-mediated amyloid-beta peptid aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed