BDBM50477185 CHEMBL239338

SMILES Cc1c(C(C)c2c(F)cccc2F)nc(N(C)C(C)C)[nH]c1=O

InChI Key InChIKey=VQJKUVSKZOTZTB-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50477185   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  30nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  40nMAssay Description:Inhibition of wild type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  40nMAssay Description:Binding affinity to wild type HIV-1 reverse transcriptase assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  80nMAssay Description:Binding affinity to HIV-1 reverse transcriptase K103N mutant assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  80nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  1.19E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477185BDBM50477185(CHEMBL239338)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed