BDBM50477518 CHEMBL436997

SMILES C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1c2ccccc2CNN(C)C1=O

InChI Key InChIKey=GMBOLUSXSNCWAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477518   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50477518(CHEMBL436997)
Affinity DataIC50: 9nMAssay Description:Inhibition of gamma secretase assessed as reduction of amyloid beta level in H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed