BDBM50478403 CHEBI:23527::CYTOCHALASIN B

SMILES C[C@@H]1CCC[C@H](/C=C/C(=O)O[C@]23[C@@H](/C=C/C1)[C@@H](C(=C)[C@H]([C@H]2[C@@H](NC3=O)Cc4ccccc4)C)O)O

InChI Key InChIKey=GBOGMAARMMDZGR-UHFFFAOYSA-N

Data  3 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50478403   

LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GLUT1 expressed in human DLD-1 cells assessed as reduction in glucose uptake by measuring decrease in ATP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 120nMAssay Description:Inhibition of human GLUT3 expressed in human GLUT1-/- DLD-1 cells assessed as reduction in glucose uptake by measuring decrease in ATP production inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 280nMAssay Description:Inhibition of human GLUT4 expressed in CHO cells assessed as reduction in glucose uptake by measuring decrease in ATP production preincubated for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 521nMAssay Description:Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human GLUT2 expressed in CHO cells assessed as reduction in fructose uptake by measuring decrease in ATP production incubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetIntegrin alpha-L(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed