BDBM50478723 CHEMBL494577

SMILES OC(=O)c1cn2[C@@H](CF)COc3c(N4C[C@@H](F)[C@@H](CNC5CC5)C4)c(F)cc(c23)c1=O

InChI Key InChIKey=CZYDTCXZKQGPJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50478723   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50478723(CHEMBL494577)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of Staphylococcus aureus MS5935 wild type DNA gyrase-mediated supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50478723(CHEMBL494577)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of quinoline-resistant Staphylococcus aureus MS5935 DNA gyrase-mediated supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed