BDBM50479316 CHEMBL515000

SMILES COc1ccc(O)c(O)c1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1N

InChI Key InChIKey=ABNAHXPUAVGYGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50479316   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50479316(CHEMBL515000)
Affinity DataIC50: 550nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50479316(CHEMBL515000)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradation after 24 hrs by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed