BDBM50479472 CHEMBL523972

SMILES Clc1cc(Oc2cc(OCc3n[nH]c4cnccc34)ccc2Cl)cc(c1)C#N

InChI Key InChIKey=BUECGHMIFPUORL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50479472   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479472(CHEMBL523972)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild type HIV1 RT polymerase by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479472(CHEMBL523972)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HIV1 RT polymerase K103N mutant by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479472(CHEMBL523972)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of HIV1 RT polymerase Y181C mutant by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed