BDBM50480064 CHEMBL494769

SMILES [H][C@]12CC[C@]([H])(Cc3cc(ccc3C1)-c1cn(cn1)-c1cccc(F)c1)[C@@]21CN(CC(F)(F)F)S(=O)(=O)N1

InChI Key InChIKey=BDNSLMRUQZNJGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480064   

TargetPresenilin-1(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50480064(CHEMBL494769)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed