BDBM50481091 CHEMBL27473

SMILES Cc1cn([C@H]2C[C@H](O)[C@@H](CO)C2)c(=O)[nH]c1=O

InChI Key InChIKey=ZOZRLTAJWLEGLG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50481091   

TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50481091(CHEMBL27473)
Affinity DataIC50: 190nMAssay Description:Inhibition of HIV1 reverse transcriptase M184V mutant-mediated viral DNA synthesis in human HOS-313 cells expressing HSV thymidine kinase assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50481091(CHEMBL27473)
Affinity DataIC50: 830nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase-mediated viral DNA synthesis in human HOS-313 cells expressing HSV thymidine kinase assessed as lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50481091(CHEMBL27473)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase M184V mutant-mediated viral DNA synthesis in human HOS cells assessed as luciferase activity treated 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Nci-Frederick

Curated by ChEMBL
LigandPNGBDBM50481091(CHEMBL27473)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase-mediated viral DNA synthesis in human HOS cells assessed as luciferase activity treated 3 hrs befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed