BDBM50481593 CHEMBL5287468

SMILES OCCn1cc(c(n1)-c1ccncc1)-c1ccc2\C(CCc2c1)=N/O

InChI Key InChIKey=DEZZLWQELQORIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481593   

TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481593(CHEMBL5287468)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of B-Raf in human A-375 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481593(CHEMBL5287468)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481593(CHEMBL5287468)
Affinity DataIC50: 63nMAssay Description:Inhibition of B-Raf in human A-375 cells assessed as reduction in pERK levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed