BDBM50482002 CHEMBL1093364

SMILES Cn1c2c(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccccc4)C(C)(C)C)cc3)ccnc2[nH]c1=O

InChI Key InChIKey=IGIJSSSOQUNKKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482002   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482002(CHEMBL1093364)
Affinity DataIC50: 164nMAssay Description:Inhibition of BRAF V600E mutant ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482002(CHEMBL1093364)
Affinity DataIC50: 215nMAssay Description:Inhibition of human BRAF V600E mutant expressed in baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed