BDBM50483256 CHEMBL1643427

SMILES COc1cc(ccc1-n1cnc(C)c1)-c1nnc2N(Cc3ccc(Cl)c(Cl)c3)CCCn12

InChI Key InChIKey=CYCWEQCEIIQZGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483256   

TargetPresenilin-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50483256(CHEMBL1643427)
Affinity DataIC50: 126nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in HEK293 cells by sandwich immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed