BDBM50484071 CHEMBL1808607

SMILES C[C@H](Nc1ccc(cn1)-c1ccc(c(c1)-c1ccccc1)-n1cnc(C)c1)c1ccc(F)cc1

InChI Key InChIKey=AJQPFWLUWDHKQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50484071   

TargetPresenilin-1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484071(CHEMBL1808607)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484071(CHEMBL1808607)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed