BDBM50484827 CHEMBL1958234::N''-(3,4-Dihydroxybenzylidene)Benzohydrazide

SMILES Oc1ccc(\C=N\NC(=O)c2ccccc2)cc1O

InChI Key InChIKey=GJRUGAROKNDLDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50484827   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50484827(N''-(3,4-Dihydroxybenzylidene)Benzohydrazide | CHE...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of Human immunodeficiency virus 1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50484827(N''-(3,4-Dihydroxybenzylidene)Benzohydrazide | CHE...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Coxsackievirus B3 3C protease expressed in Escherichia coli BL21 (DE3) preincubated for 5 mins followed by addition of NMA-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50484827(N''-(3,4-Dihydroxybenzylidene)Benzohydrazide | CHE...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ribonuclease H activity of HIV1 reverse transcriptase using as poly(dC)-[3H]poly(rG) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed